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PLK1 protects intestinal barrier function during sepsis by targeting mitochondrial dynamics through TANK-NF-κB signalling

BACKGROUND: Intestinal barrier integrity in the pathogenesis of sepsis is critical. Despite an abundance of evidence, the molecular mechanism of the intestinal barrier in sepsis pathology remains unclear. Here, we report a protective role of polo-like kinase 1 (PLK1) in intestinal barrier integrity...

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Detalles Bibliográficos
Autores principales:	Cao, Ying-Ya, Zhang, Yuan, Gerile, Wuyun, Guo, Yan, Wu, Li-Na, Wu, Li-Li, Song, Kai, Lu, Wei-Hua, Yu, Jian-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801534/ https://www.ncbi.nlm.nih.gov/pubmed/36581806 http://dx.doi.org/10.1186/s10020-022-00597-z

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