DNA methylation in human gastric epithelial cells defines regional identity without restricting lineage plasticity

BACKGROUND: Epigenetic modifications in mammalian DNA are commonly manifested by DNA methylation. In the stomach, altered DNA methylation patterns have been observed following chronic Helicobacter pylori infections and in gastric cancer. In the context of epigenetic regulation, the regional nature o...

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Detalles Bibliográficos
Autores principales: Fritsche, Kristin, Boccellato, Francesco, Schlaermann, Philipp, Koeppel, Max, Denecke, Christian, Link, Alexander, Malfertheiner, Peter, Gut, Ivo, Meyer, Thomas F., Berger, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801550/
https://www.ncbi.nlm.nih.gov/pubmed/36585699
http://dx.doi.org/10.1186/s13148-022-01406-4

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