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Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study

BACKGROUND: Several studies worldwide have investigated household product poisoning. We conducted a toxico-clinical study on the two-year prevalence of poisoning with household products. METHODS: This cross-sectional study was performed in Khorshid Hospital, the main referral center for poisoning ca...

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Autores principales: Eizadi-Mood, Nastaran, Lalehzar, Sahar Sadat, Niknam, Sara, Mahvari, Razieh, Mirmoghtadaee, Parisa, Meamar, Rokhsareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801583/
https://www.ncbi.nlm.nih.gov/pubmed/36581950
http://dx.doi.org/10.1186/s40360-022-00640-z
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author Eizadi-Mood, Nastaran
Lalehzar, Sahar Sadat
Niknam, Sara
Mahvari, Razieh
Mirmoghtadaee, Parisa
Meamar, Rokhsareh
author_facet Eizadi-Mood, Nastaran
Lalehzar, Sahar Sadat
Niknam, Sara
Mahvari, Razieh
Mirmoghtadaee, Parisa
Meamar, Rokhsareh
author_sort Eizadi-Mood, Nastaran
collection PubMed
description BACKGROUND: Several studies worldwide have investigated household product poisoning. We conducted a toxico-clinical study on the two-year prevalence of poisoning with household products. METHODS: This cross-sectional study was performed in Khorshid Hospital, the main referral center for poisoning cases in Isfahan, affiliated to Isfahan University of Medical Sciences, Isfahan, central Iran. All patients with intentional or unintentional household substance poisoning, referring to the poisoning emergency center of the hospital, were evaluated with respect to epidemiological and toxico-clinical features and outcomes. RESULTS: During the study period, 5946 patients were hospitalized, of which 83 (1.39%) had been poisoned with household products including 48 (57.8%) men and 35 (42.2%) women with a mean ± SD age of 34.40 ± 17.71 years. Most patients (54.2%) were in the 20–40-year-old age group. Accidental poisoning (63.9%) was the most common type of exposure (P = 0.02) predominantly in men (57.8%, P = 0.51). The most common household products were sodium hypochlorite (32.53%) followed by petroleum hydrocarbon (21.68%). Most of the accidental poisonings (77.8%) were due to petroleum hydrocarbon. 59% of cases were poisoned at home (P < 0.0001). No patient died. CONCLUSION: Household products were not common means of poisoning in our referral center. Sodium hypochlorite and petroleum hydrocarbon were the most common substances. Most of the patients were men with accidental exposure at home. Because of the availability of the household product, the frequency and outcomes may be varied in different societies.
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spelling pubmed-98015832022-12-31 Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study Eizadi-Mood, Nastaran Lalehzar, Sahar Sadat Niknam, Sara Mahvari, Razieh Mirmoghtadaee, Parisa Meamar, Rokhsareh BMC Pharmacol Toxicol Research BACKGROUND: Several studies worldwide have investigated household product poisoning. We conducted a toxico-clinical study on the two-year prevalence of poisoning with household products. METHODS: This cross-sectional study was performed in Khorshid Hospital, the main referral center for poisoning cases in Isfahan, affiliated to Isfahan University of Medical Sciences, Isfahan, central Iran. All patients with intentional or unintentional household substance poisoning, referring to the poisoning emergency center of the hospital, were evaluated with respect to epidemiological and toxico-clinical features and outcomes. RESULTS: During the study period, 5946 patients were hospitalized, of which 83 (1.39%) had been poisoned with household products including 48 (57.8%) men and 35 (42.2%) women with a mean ± SD age of 34.40 ± 17.71 years. Most patients (54.2%) were in the 20–40-year-old age group. Accidental poisoning (63.9%) was the most common type of exposure (P = 0.02) predominantly in men (57.8%, P = 0.51). The most common household products were sodium hypochlorite (32.53%) followed by petroleum hydrocarbon (21.68%). Most of the accidental poisonings (77.8%) were due to petroleum hydrocarbon. 59% of cases were poisoned at home (P < 0.0001). No patient died. CONCLUSION: Household products were not common means of poisoning in our referral center. Sodium hypochlorite and petroleum hydrocarbon were the most common substances. Most of the patients were men with accidental exposure at home. Because of the availability of the household product, the frequency and outcomes may be varied in different societies. BioMed Central 2022-12-29 /pmc/articles/PMC9801583/ /pubmed/36581950 http://dx.doi.org/10.1186/s40360-022-00640-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Eizadi-Mood, Nastaran
Lalehzar, Sahar Sadat
Niknam, Sara
Mahvari, Razieh
Mirmoghtadaee, Parisa
Meamar, Rokhsareh
Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
title Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
title_full Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
title_fullStr Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
title_full_unstemmed Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
title_short Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
title_sort toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801583/
https://www.ncbi.nlm.nih.gov/pubmed/36581950
http://dx.doi.org/10.1186/s40360-022-00640-z
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