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Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase

BACKGROUND: In neuroblastoma, hyperactivation of the PI3K signaling pathway has been correlated with aggressive neuroblastomas, suggesting PI3Ks as promising targets for the treatment of neuroblastoma. However, the oncogenic roles of individual PI3K isoforms in neuroblastoma remain elusive. RESULTS:...

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Detalles Bibliográficos
Autores principales:	Guo, Yue, Guo, Donghao, Zhang, Shaoting, Zhang, Yuan, He, Xiaoyan, Jiang, Xiaohua, Chan, Andrew Man-Lok, Zou, Lin, Sun, Jianmin, Zhao, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801621/ https://www.ncbi.nlm.nih.gov/pubmed/36585695 http://dx.doi.org/10.1186/s13578-022-00946-9

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