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Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review

BACKGROUND: Nocardia cyriacigeorgica is one of the most common Nocardia species found in human infections, recently reclassified. Even though Nocardia may affect all organs by hematogenous dissemination, bacteremia are uncommon. Among all possible dissemination sites, the involvement of the adrenal...

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Autores principales: Saunier, Florian, Grange, Sylvain, Rigaill, Josselin, Lutz, Marie-France, Gagneux-Brunon, Amandine, Botelho-Nevers, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801643/
https://www.ncbi.nlm.nih.gov/pubmed/36581805
http://dx.doi.org/10.1186/s12879-022-07839-9
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author Saunier, Florian
Grange, Sylvain
Rigaill, Josselin
Lutz, Marie-France
Gagneux-Brunon, Amandine
Botelho-Nevers, Elisabeth
author_facet Saunier, Florian
Grange, Sylvain
Rigaill, Josselin
Lutz, Marie-France
Gagneux-Brunon, Amandine
Botelho-Nevers, Elisabeth
author_sort Saunier, Florian
collection PubMed
description BACKGROUND: Nocardia cyriacigeorgica is one of the most common Nocardia species found in human infections, recently reclassified. Even though Nocardia may affect all organs by hematogenous dissemination, bacteremia are uncommon. Among all possible dissemination sites, the involvement of the adrenal glands is particularly rare. CASE PRESENTATION: We report here a rare case of Nocardia disseminated infection with notably bacteremia and adrenal gland abscess, in a 77-years-old immunocompetent man. Adrenal gland abscess diagnosis was made by imaging (computerized tomography, magnetic resonance and positron emission tomography scan). A complete regression of all lesions including the left adrenal gland was obtained after 6 months of antibiotics. A review of literature was also performed. CONCLUSION: Nocardia bacteremia is a rare event but blood cultures may help to improve detection of Nocardia spp. in a non-invasive way. Adrenal abscess due to Nocardia spp. is very rare with only fourteen cases reported in the literature, but it is a true cause of adrenal masses. Our report suggests that clinician should be aware of this rare location and prioritize a non-invasive diagnosis strategy.
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spelling pubmed-98016432022-12-31 Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review Saunier, Florian Grange, Sylvain Rigaill, Josselin Lutz, Marie-France Gagneux-Brunon, Amandine Botelho-Nevers, Elisabeth BMC Infect Dis Case Report BACKGROUND: Nocardia cyriacigeorgica is one of the most common Nocardia species found in human infections, recently reclassified. Even though Nocardia may affect all organs by hematogenous dissemination, bacteremia are uncommon. Among all possible dissemination sites, the involvement of the adrenal glands is particularly rare. CASE PRESENTATION: We report here a rare case of Nocardia disseminated infection with notably bacteremia and adrenal gland abscess, in a 77-years-old immunocompetent man. Adrenal gland abscess diagnosis was made by imaging (computerized tomography, magnetic resonance and positron emission tomography scan). A complete regression of all lesions including the left adrenal gland was obtained after 6 months of antibiotics. A review of literature was also performed. CONCLUSION: Nocardia bacteremia is a rare event but blood cultures may help to improve detection of Nocardia spp. in a non-invasive way. Adrenal abscess due to Nocardia spp. is very rare with only fourteen cases reported in the literature, but it is a true cause of adrenal masses. Our report suggests that clinician should be aware of this rare location and prioritize a non-invasive diagnosis strategy. BioMed Central 2022-12-29 /pmc/articles/PMC9801643/ /pubmed/36581805 http://dx.doi.org/10.1186/s12879-022-07839-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Saunier, Florian
Grange, Sylvain
Rigaill, Josselin
Lutz, Marie-France
Gagneux-Brunon, Amandine
Botelho-Nevers, Elisabeth
Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review
title Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review
title_full Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review
title_fullStr Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review
title_full_unstemmed Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review
title_short Bacteremia and adrenal gland abscess due to Nocardia cyriacigeorgica: a case report and review
title_sort bacteremia and adrenal gland abscess due to nocardia cyriacigeorgica: a case report and review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801643/
https://www.ncbi.nlm.nih.gov/pubmed/36581805
http://dx.doi.org/10.1186/s12879-022-07839-9
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