Genome-wide placental DNA methylations in fetal overgrowth and associations with leptin, adiponectin and fetal growth factors

BACKGROUND: Fetal overgrowth “programs” an elevated risk of type 2 diabetes in adulthood. Epigenetic alterations may be a mechanism in programming the vulnerability. We sought to characterize genome-wide alterations in placental gene methylations in fetal overgrowth and the associations with metabol...

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Detalles Bibliográficos
Autores principales: Yang, Meng-Nan, Huang, Rong, Zheng, Tao, Dong, Yu, Wang, Wen-Juan, Xu, Ya-Jie, Mehra, Vrati, Zhou, Guang-Di, Liu, Xin, He, Hua, Fang, Fang, Li, Fei, Fan, Jian-Gao, Zhang, Jun, Ouyang, Fengxiu, Briollais, Laurent, Li, Jiong, Luo, Zhong-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801645/
https://www.ncbi.nlm.nih.gov/pubmed/36585686
http://dx.doi.org/10.1186/s13148-022-01412-6

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