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C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus

Infections caused by Mycobacterium abscessus are difficult to treat due to its intrinsic resistance to most antibiotics. Formation of biofilms and the capacity of M. abscessus to survive inside host phagocytes further complicate eradication. Herein, we explored whether addition of a carbamate-linked...

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Detalles Bibliográficos
Autores principales:	Paulowski, Laura, Beckham, Katherine S H, Johansen, Matt D, Berneking, Laura, Van, Nhi, Degefu, Yonatan, Staack, Sonja, Sotomayor, Flor Vasquez, Asar, Lucia, Rohde, Holger, Aldridge, Bree B, Aepfelbacher, Martin, Parret, Annabel, Wilmanns, Matthias, Kremer, Laurent, Combrink, Keith, Maurer, Florian P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Biological, Health, and Medical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802118/ https://www.ncbi.nlm.nih.gov/pubmed/36714853 http://dx.doi.org/10.1093/pnasnexus/pgac130

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