Performance Characteristics of a Clinical Decision Support Tool for Disease Complications in Crohn’s Disease

BACKGROUND: Patients with Crohn’s disease (CD) are at risk of complications. Performance characteristics of a decision support tool assessing the risk of CD complications were evaluated. METHODS: CDPATH (formerly called the Personalized Risk and Outcome Prediction Tool [PROSPECT]) was calibrated and...

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Detalles Bibliográficos
Autores principales: Siegel, Corey A, Siegel, Lori S, Dubinsky, Marla C, Targan, Stephan, Braun, Jonathan, Landers, Carol, Bilsborough, Janine, Princen, Fred, Lasch, Karen, Candela, Ninfa, McGovern, Dermot P B, Dervieux, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Observations and Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802159/
https://www.ncbi.nlm.nih.gov/pubmed/36777269
http://dx.doi.org/10.1093/crocol/otab074
Descripción
Sumario:BACKGROUND: Patients with Crohn’s disease (CD) are at risk of complications. Performance characteristics of a decision support tool assessing the risk of CD complications were evaluated. METHODS: CDPATH (formerly called the Personalized Risk and Outcome Prediction Tool [PROSPECT]) was calibrated and validated in 2 cohorts. Tool prediction of disease characteristics was assessed using Cox regression and Harrell’s C-statistic. RESULTS: All associations of CD complications and CDPATH components were significant except perianal location. There was a significant association between individualized risk assessment scores and CD complications in both cohorts. CONCLUSION: CDPATH is validated as a clinical decision support tool for assessing the risk of CD complications.

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