Stochastic activation of a family of TetR type transcriptional regulators controls phenotypic heterogeneity in Acinetobacter baumannii

Phenotypic heterogeneity is an important mechanism for regulating bacterial virulence, where a single regulatory switch is typically activated to generate virulent and avirulent subpopulations. The opportunistic pathogen Acinetobacter baumannii can transition at high frequency between virulent opaqu...

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Detalles Bibliográficos
Autores principales: Pérez-Varela, María, Tierney, Aimee R P, Dawson, Emma, Hutcheson, Anna R, Tipton, Kyle A, Anderson, Sarah E, Haldopoulos, Marina E, Song, Shaina, Tomlinson, Brooke R, Shaw, Lindsey N, Weiss, David S, Kim, Minsu, Rather, Philip N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802203/
https://www.ncbi.nlm.nih.gov/pubmed/36704122
http://dx.doi.org/10.1093/pnasnexus/pgac231

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