The Clinical Characteristics and Treatment Outcomes of Concomitant Eosinophilic Esophagitis and Inflammatory Bowel Disease

BACKGROUND: The clinical characteristics and treatment outcomes in patients with eosinophilic esophagitis (EoE) and inflammatory bowel disease (IBD) have not been extensively investigated. METHODS: We determined treatment outcomes and frequencies of disease-related complications in patients with EoE...

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Detalles Bibliográficos
Autores principales: Urquhart, Siri A, Quinn, Kevin P, Ravi, Karthik, Loftus, Edward V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Observations and Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802462/
https://www.ncbi.nlm.nih.gov/pubmed/36778939
http://dx.doi.org/10.1093/crocol/otab018
Descripción
Sumario:BACKGROUND: The clinical characteristics and treatment outcomes in patients with eosinophilic esophagitis (EoE) and inflammatory bowel disease (IBD) have not been extensively investigated. METHODS: We determined treatment outcomes and frequencies of disease-related complications in patients with EoE and IBD. RESULTS: Among 69 patients who met inclusion criteria, 39 (56.5%) had a diagnosis of Crohn disease. Clinical and histologic response rates to proton pump inhibitors and topical steroids were 25.9% and 24.4%, respectively. CONCLUSIONS: Lower than expected clinical and histologic response rates for EoE suggest the combination of EoE and IBD is a medically refractory phenotype with more difficult to treat EoE.

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