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Role of Pyroptosis in Acetaminophen-Induced Hepatotoxicity

Acetaminophen (APAP) is a widely used pain reliever that can cause liver injury or liver failure in response to an overdose. Understanding the mechanisms of APAP-induced cell death is critical for identifying new therapeutic targets. In this respect it was hypothesized that hepatocytes die by oncoti...

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Detalles Bibliográficos
Autores principales: Jaeschke, Hartmut, Umbaugh, David S., Ramachandran, Anup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802630/
https://www.ncbi.nlm.nih.gov/pubmed/36588962
http://dx.doi.org/10.3390/livers2040032

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