Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey

With the ultimate goal of developing a more representative animal model of Alzheimer's disease (AD), two female amyloid-β-(Aβ) precursor protein-transgenic (APPtg) rhesus monkeys were generated by lentiviral transduction of the APP gene into rhesus oocytes, followed by in vitro fertilization an...

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Detalles Bibliográficos
Autores principales: Chan, Anthony W.S., Cho, In Ki, Li, Chun-Xia, Zhang, Xiaodong, Patel, Sudeep, Rusnak, Rebecca, Raper, Jessica, Bachevalier, Jocelyne, Moran, Sean P., Chi, Tim, Cannon, Katherine H., Hunter, Carissa E., Martin, Ryan C., Xiao, Hailian, Yang, Shang-Hsun, Gumber, Sanjeev, Herndon, James G., Rosen, Rebecca F., Hu, William T., Lah, James J., Levey, Allan I., Smith, Yoland, Walker, Lary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9802652/
https://www.ncbi.nlm.nih.gov/pubmed/36589695
http://dx.doi.org/10.1016/j.nbas.2022.100044

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