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Identification of C. elegans ASNA-1 domains and tissue requirements that differentially influence platinum sensitivity and growth control
ASNA1 plays an essential role in cisplatin chemotherapy response, type 2 diabetes, and heart disease. It is also an important biomarker in the treatment response of many diseases. Biochemically, ASNA1 has two mutually exclusive redox-modulated roles: a tail-anchored protein (TAP) targeting function...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803280/ https://www.ncbi.nlm.nih.gov/pubmed/36480541 http://dx.doi.org/10.1371/journal.pgen.1010538 |