Cargando…

Identification of C. elegans ASNA-1 domains and tissue requirements that differentially influence platinum sensitivity and growth control

ASNA1 plays an essential role in cisplatin chemotherapy response, type 2 diabetes, and heart disease. It is also an important biomarker in the treatment response of many diseases. Biochemically, ASNA1 has two mutually exclusive redox-modulated roles: a tail-anchored protein (TAP) targeting function...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raj, Dorota, Podraza-Farhanieh, Agnieszka, Gallego, Pablo, Kao, Gautam, Naredi, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803280/ https://www.ncbi.nlm.nih.gov/pubmed/36480541 http://dx.doi.org/10.1371/journal.pgen.1010538

Ejemplares similares

A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans
por: Podraza-Farhanieh, Agnieszka, et al.
Publicado: (2023)

Alternative redox forms of ASNA-1 separate insulin signaling from tail-anchored protein targeting and cisplatin resistance in C. elegans
por: Raj, Dorota, et al.
Publicado: (2021)

Cisplatin toxicity is counteracted by the activation of the p38/ATF-7 signaling pathway in post-mitotic C. elegans
por: Raj, Dorota, et al.
Publicado: (2023)

Mitochondrial Function Is Required for Secretion of DAF-28/Insulin in C. elegans
por: Billing, Ola, et al.
Publicado: (2011)

The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival
por: Norlin, Stefan, et al.
Publicado: (2018)

Depletion of the ER chaperone ENPL-1 sensitizes C. elegans to the anticancer drug cisplatin
por: Natarajan, Balasubramanian, et al.
Publicado: (2013)

A Directed RNAi Screen Based on Larval Growth Arrest Reveals New Modifiers of C. elegans Insulin Signaling
por: Billing, Ola, et al.
Publicado: (2012)

Molecular characterization and analysis of the ATPase ASNA1 homolog gene of Eimeria tenella in a drug sensitive strain and drug resistant strains
por: Yu, Yu, et al.
Publicado: (2021)

Asna1/TRC40 that mediates membrane insertion of tail-anchored proteins is required for efficient release of Herpes simplex virus 1 virions
por: Ott, Melanie, et al.
Publicado: (2016)

WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane
por: Vilardi, Fabio, et al.
Publicado: (2011)

VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase
por: Baron, Yorann, et al.
Publicado: (2014)

Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins
por: Morgens, David W, et al.
Publicado: (2019)

Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of Tail-Anchored Proteins, Cause Rapidly Progressive Pediatric Cardiomyopathy
por: Verhagen, Judith M.A., et al.
Publicado: (2019)

N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans
por: Shimizu, Tatsuhiro, et al.
Publicado: (2019)

Epidermal Remodeling in Caenorhabditis elegans Dauers Requires the Nidogen Domain Protein DEX-1
por: Flatt, Kristen M., et al.
Publicado: (2019)

The CRTC-1 transcriptional domain is required for COMPASS complex-mediated longevity in C. elegans
por: Silva-García, Carlos G., et al.
Publicado: (2023)

BK channel clustering is required for normal behavioral alcohol sensitivity in C. elegans
por: Oh, Kelly H., et al.
Publicado: (2019)

The nutritional requirements of Caenorhabditis elegans
por: Zečić, Aleksandra, et al.
Publicado: (2019)

C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain
por: Soloviev, Alexander, et al.
Publicado: (2011)

Markers of Oxidative Stress and Inflammation in Ascites and Plasma in Patients with Platinum-Sensitive, Platinum-Resistant, and Platinum-Refractory Epithelial Ovarian Cancer
por: Cantón-Romero, Juan Carlos, et al.
Publicado: (2017)

PMMA-Based Wafer-Bonded Capacitive Micromachined Ultrasonic Transducer for Underwater Applications
por: Ahmad, Mansoor, et al.
Publicado: (2019)

FAH Domain Containing Protein 1 (FAHD-1) Is Required for Mitochondrial Function and Locomotion Activity in C. elegans
por: Taferner, Andrea, et al.
Publicado: (2015)

IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans
por: Kuo, Cheng-Ju, et al.
Publicado: (2020)

Identification of interneurons required for the aversive response of Caenorhabditis elegans to graphene oxide
por: Xiao, Guosheng, et al.
Publicado: (2018)

Bevacizumab in combination with chemotherapy in platinum-sensitive ovarian cancer
por: Della Pepa, Chiara, et al.
Publicado: (2014)

Genomic landscape of platinum resistant and sensitive testicular cancers
por: Loveday, Chey, et al.
Publicado: (2020)

An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy
por: Liu, Gongyuan, et al.
Publicado: (2023)

CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans
por: Warner, Adam, et al.
Publicado: (2013)

Acentrosomal spindle assembly and maintenance in Caenorhabditis elegans oocytes requires a kinesin-12 nonmotor microtubule interaction domain
por: Wolff, Ian D., et al.
Publicado: (2022)

Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells
por: Roberts, D, et al.
Publicado: (2005)

Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system
por: Yoshimoto, Yuki, et al.
Publicado: (2017)

Tissue organ distribution and behavioral effects of platinum following acute and repeated exposure of the mouse to platinum sulfate.
por: Lown, B A, et al.
Publicado: (1980)

Real-time assessment of platinum sensitivity of primary culture from a patient with ovarian cancer with extensive metastasis and the platinum sensitivity enhancing effect by metformin
por: Liu, Yingzhao, et al.
Publicado: (2018)

Caenorhabditis elegans oocyte meiotic spindle pole assembly requires microtubule severing and the calponin homology domain protein ASPM-1
por: Connolly, Amy A., et al.
Publicado: (2014)

Bevacizumab in combination with chemotherapy in platinum-sensitive ovarian cancer [Corrigendum]
Publicado: (2014)

Epimorphin-Induced MET Sensitizes Ovarian Cancer Cells to Platinum
por: Yew, Kok-Hooi, et al.
Publicado: (2013)

Platinum-Sensitive Recurrence in Ovarian Cancer: The Role of Tumor Microenvironment
por: Chien, Jeremy, et al.
Publicado: (2013)

Cisplatin Protein Binding Partners and Their Relevance for Platinum Drug Sensitivity
por: Möltgen, Sophie, et al.
Publicado: (2020)

Maintenance with Trabectedin in the Treatment of Platinum-Sensitive Recurrent Ovarian Cancer
por: Guerra Alía, Eva María, et al.
Publicado: (2019)

Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer
por: Criscuolo, Daniela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1pkaacs3broqo4au97mrqn70gd