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Identification of C. elegans ASNA-1 domains and tissue requirements that differentially influence platinum sensitivity and growth control

ASNA1 plays an essential role in cisplatin chemotherapy response, type 2 diabetes, and heart disease. It is also an important biomarker in the treatment response of many diseases. Biochemically, ASNA1 has two mutually exclusive redox-modulated roles: a tail-anchored protein (TAP) targeting function...

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Detalles Bibliográficos
Autores principales:	Raj, Dorota, Podraza-Farhanieh, Agnieszka, Gallego, Pablo, Kao, Gautam, Naredi, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803280/ https://www.ncbi.nlm.nih.gov/pubmed/36480541 http://dx.doi.org/10.1371/journal.pgen.1010538

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