Cargando…

Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity

Vascular dysfunction and capillary leak are common in critically ill COVID-19 patients, but identification of endothelial pathways involved in COVID-19 pathogenesis has been limited. Angiopoietin-like 4 (ANGPTL4) is a protein secreted in response to hypoxic and nutrient-poor conditions that has a va...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhatraju, Pavan K., Morrell, Eric D., Stanaway, Ian B., Sathe, Neha A., Srivastava, Avantika, Postelnicu, Radu, Green, Richard, Andrews, Adair, Gonzalez, Martin, Kratochvil, Christopher J., Kumar, Vishakha K., Hsiang, Tien-Ying, Gale, Michael, Anesi, George L., Wyles, David, Broadhurst, M. Jana, Brett-Major, David, Mukherjee, Vikramjit, Sevransky, Jonathan E., Landsittel, Douglas, Hung, Chi, Altemeier, William A., Gharib, Sina A., Uyeki, Timothy M., Cobb, J. Perren, Liebler, Janice M., Crosslin, David R., Jarvik, Gail P., Segal, Leopoldo N., Evans, Laura, Mikacenic, Carmen, Wurfel, Mark M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Observational Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803343/ https://www.ncbi.nlm.nih.gov/pubmed/36600780 http://dx.doi.org/10.1097/CCE.0000000000000827

Ejemplares similares

Perceived Hospital Stress, Severe Acute Respiratory Syndrome Coronavirus 2 Activity, and Care Process Temporal Variance During the COVID-19 Pandemic*
por: Anesi, George L., et al.
Publicado: (2023)

Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approach
por: Sathe, Neha A., et al.
Publicado: (2023)

Reply to Walter and Reyfman: Transcriptomic Analysis of Alveolar Immune Cells in Acute Respiratory Distress Syndrome: To Lump or to Split?
por: Morrell, Eric D., et al.
Publicado: (2019)

Plasma Soluble CD14 Subtype Levels Are Associated With Clinical Outcomes in Critically Ill Subjects With Coronavirus Disease 2019
por: Mabrey, F. Linzee, et al.
Publicado: (2021)

Plasma Interleukin-6 Predicts Clinical Decline After Completion of Dexamethasone Therapy in Severe COVID-19
por: Mabrey, F. Linzee, et al.
Publicado: (2022)

Hyaluronic acid is associated with organ dysfunction in acute respiratory distress syndrome
por: Esposito, Anthony J., et al.
Publicado: (2017)

Identification of persistent and resolving subphenotypes of acute hypoxemic respiratory failure in two independent cohorts
por: Sathe, Neha A., et al.
Publicado: (2021)

Associations between single nucleotide polymorphisms in the FAS pathway and acute kidney injury
por: Bhatraju, Pavan, et al.
Publicado: (2015)

Endotracheal aspirates contain a limited number of lower respiratory tract immune cells
por: Orlov, Marika, et al.
Publicado: (2021)

Alveolar MMP28 is associated with clinical outcomes and measures of lung injury in acute respiratory distress syndrome
por: Morrell, Eric D., et al.
Publicado: (2020)

Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes
por: Bhatraju, Pavan K., et al.
Publicado: (2020)

Comparison of Clinical Features and Outcomes in Critically Ill Patients Hospitalized with COVID-19 versus Influenza
por: Cobb, Natalie L., et al.
Publicado: (2021)

Th17 cells are associated with protection from ventilator associated pneumonia
por: Orlov, Marika, et al.
Publicado: (2017)

Trajectory of Kidney Function: The Canary in Sepsis
por: Bhatraju, Pavan K., et al.
Publicado: (2020)

Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations
por: Helms, Louisa, et al.
Publicado: (2021)

Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype
por: Bhatraju, Pavan K., et al.
Publicado: (2017)

Mitochondrial N-formyl methionine peptides contribute to exaggerated neutrophil activation in patients with COVID-19
por: Kuley, Runa, et al.
Publicado: (2023)

Building the Pyramids: A Perspective on Creating and Upscaling a Critical Care Workforce at a Public Hospital During the Coronavirus Disease 2019 Pandemic in New York City
por: Bhatt, Alok, et al.
Publicado: (2020)

Differences between Children and Adults with COVID-19: It’s Right under Our Nose
por: Morrell, Eric D., et al.
Publicado: (2021)

Comparison of host endothelial, epithelial and inflammatory response in ICU patients with and without COVID-19: a prospective observational cohort study
por: Bhatraju, Pavan K., et al.
Publicado: (2021)

Differential absolute plasma IL-6 concentrations between two immunoassay platforms in intensive care unit patients with COVID-19
por: Bhatraju, Pavan K, et al.
Publicado: (2023)

Assessment of kidney proximal tubular secretion in critical illness
por: Bhatraju, Pavan K., et al.
Publicado: (2021)

Presence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus-2 on Admission Is Associated With Decreased Mortality in COVID-19 Critical Illness
por: Mabrey, F. Linzee, et al.
Publicado: (2022)

Prone positioning for non-intubated hypoxaemic patients with COVID-19: cheap, easy and makes sense, but does it work?
por: Morrell, Eric D., et al.
Publicado: (2022)

Variation in the TLR10/TLR1/TLR6 Locus is the Major Genetic Determinant of Inter-Individual Difference in TLR1/2-Mediated Responses
por: Mikacenic, Carmen, et al.
Publicado: (2012)

Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator-associated pneumonia
por: Mikacenic, Carmen, et al.
Publicado: (2018)

Critical Elements of an Mpox Vaccination Model at the Largest Public Health Hospital System in the United States
por: Piccolo, Anthony J. Lo, et al.
Publicado: (2023)

Copy number variation analysis in the context of electronic medical records and large-scale genomics consortium efforts
por: Connolly, John J., et al.
Publicado: (2014)

TLRs in COVID-19: How they drive immunopathology and the rationale for modulation
por: Mabrey, F. Linzee, et al.
Publicado: (2021)

Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock
por: Melendez, Elliot, et al.
Publicado: (2019)

COPD disease severity and innate immune response to pathogen-associated molecular patterns
por: Fan, Vincent S, et al.
Publicado: (2016)

Association of markers of endothelial dysregulation Ang1 and Ang2 with acute kidney injury in critically ill patients
por: Robinson-Cohen, Cassianne, et al.
Publicado: (2016)

Genome-wide Association Study for AKI
por: Bhatraju, Pavan K., et al.
Publicado: (2023)

Transglutaminase 2, a Novel Regulator of Eicosanoid Production in Asthma Revealed by Genome-Wide Expression Profiling of Distinct Asthma Phenotypes
por: Hallstrand, Teal S., et al.
Publicado: (2010)

Covid-19 in Critically Ill Patients in the Seattle Region — Case Series
por: Bhatraju, Pavan K., et al.
Publicado: (2020)

25-Hydroxycholesterol exacerbates vascular leak during acute lung injury
por: Madenspacher, Jennifer H., et al.
Publicado: (2023)

Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia
por: Mabrey, F. Linzee, et al.
Publicado: (2023)

Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness
por: Mikacenic, Carmen, et al.
Publicado: (2015)

The transcriptional and phenotypic characteristics that define alveolar macrophage subsets in acute hypoxemic respiratory failure
por: Morrell, Eric D., et al.
Publicado: (2023)

Biomarker Signatures of Severe Acute Kidney Injury in a Critically Ill Cohort of COVID-19 and Non-COVID-19 Acute Respiratory Illness
por: Sathe, Neha A., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nocahtuna34t4omr80jqs1ms10