Cargando…
An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report
Embryonal rhabdomyosarcoma (ERMS) is a major subtype of rhabdomyosarcoma, mainly affect children. There is seldom report for perineal ERMS in adults, since its rare location and the age. PATIENT CONCERNS: A 20-year old male adult was admitted due to the perineal mass. DIAGNOSES: Diagnosis by histopa...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803527/ https://www.ncbi.nlm.nih.gov/pubmed/36596039 http://dx.doi.org/10.1097/MD.0000000000032529 |
_version_ | 1784861907224625152 |
---|---|
author | Qu, Sifeng Li, Weiwei Yao, Yuan Huang, Huangwei |
author_facet | Qu, Sifeng Li, Weiwei Yao, Yuan Huang, Huangwei |
author_sort | Qu, Sifeng |
collection | PubMed |
description | Embryonal rhabdomyosarcoma (ERMS) is a major subtype of rhabdomyosarcoma, mainly affect children. There is seldom report for perineal ERMS in adults, since its rare location and the age. PATIENT CONCERNS: A 20-year old male adult was admitted due to the perineal mass. DIAGNOSES: Diagnosis by histopathological examination of the biopsy sample was ERMS. Magnetic resonance imaging showed the tumor was found in the perineal region, with metastasis to pelvic cavity, right testis, lymph nodes and bone. INTERVENTIONS: The patient received Isophosphamide and Epirubicin for 4 cycles, followed by Irinotecan and Vindesine Sulfate for 2 cycles, then cisplatin, Dacarbazine and Apatinib for 3 cycles. OUTCOME: The patient showed no response to chemotherapy. LESSONS: Perineal ERMS in adults is very rare. There is still no standard therapy for adult ERMS. Personalized therapy might be promising treatment for each individual. |
format | Online Article Text |
id | pubmed-9803527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-98035272023-01-03 An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report Qu, Sifeng Li, Weiwei Yao, Yuan Huang, Huangwei Medicine (Baltimore) 5700 Embryonal rhabdomyosarcoma (ERMS) is a major subtype of rhabdomyosarcoma, mainly affect children. There is seldom report for perineal ERMS in adults, since its rare location and the age. PATIENT CONCERNS: A 20-year old male adult was admitted due to the perineal mass. DIAGNOSES: Diagnosis by histopathological examination of the biopsy sample was ERMS. Magnetic resonance imaging showed the tumor was found in the perineal region, with metastasis to pelvic cavity, right testis, lymph nodes and bone. INTERVENTIONS: The patient received Isophosphamide and Epirubicin for 4 cycles, followed by Irinotecan and Vindesine Sulfate for 2 cycles, then cisplatin, Dacarbazine and Apatinib for 3 cycles. OUTCOME: The patient showed no response to chemotherapy. LESSONS: Perineal ERMS in adults is very rare. There is still no standard therapy for adult ERMS. Personalized therapy might be promising treatment for each individual. Lippincott Williams & Wilkins 2022-12-30 /pmc/articles/PMC9803527/ /pubmed/36596039 http://dx.doi.org/10.1097/MD.0000000000032529 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 5700 Qu, Sifeng Li, Weiwei Yao, Yuan Huang, Huangwei An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report |
title | An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report |
title_full | An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report |
title_fullStr | An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report |
title_full_unstemmed | An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report |
title_short | An uncommon perineal embryonal rhabdomyosarcoma in adult: A case report |
title_sort | uncommon perineal embryonal rhabdomyosarcoma in adult: a case report |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803527/ https://www.ncbi.nlm.nih.gov/pubmed/36596039 http://dx.doi.org/10.1097/MD.0000000000032529 |
work_keys_str_mv | AT qusifeng anuncommonperinealembryonalrhabdomyosarcomainadultacasereport AT liweiwei anuncommonperinealembryonalrhabdomyosarcomainadultacasereport AT yaoyuan anuncommonperinealembryonalrhabdomyosarcomainadultacasereport AT huanghuangwei anuncommonperinealembryonalrhabdomyosarcomainadultacasereport AT qusifeng uncommonperinealembryonalrhabdomyosarcomainadultacasereport AT liweiwei uncommonperinealembryonalrhabdomyosarcomainadultacasereport AT yaoyuan uncommonperinealembryonalrhabdomyosarcomainadultacasereport AT huanghuangwei uncommonperinealembryonalrhabdomyosarcomainadultacasereport |