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Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

Changes in cellular bioenergetics such as mitochondrial respiration and glycolysis may play a role in the pathogenesis of various diseases including type 1 diabetes (T1D). We used Seahorse extracellular flux technology to analyse the efficiency of glycolysis and mitochondrial oxidative phosphorylati...

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Detalles Bibliográficos
Autores principales:	Lopes de Melo, Joana Mendes, Laursen, Jens Christian, Søndergaard-Heinrich, Niels, Bull Rasmussen, Ida Kirstine, Hansen, Christian Stevns, Frimodt-Møller, Marie, Rossing, Peter, Størling, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803776/ https://www.ncbi.nlm.nih.gov/pubmed/36593831 http://dx.doi.org/10.1016/j.heliyon.2022.e12304

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