Enhancement of glycolysis-dependent DNA repair regulated by FOXO1 knockdown via PFKFB3 attenuates hyperglycemia-induced endothelial oxidative stress injury

The accumulation of DNA damage induced by oxidative stress is a crucial pathogenic factor of endothelial loss in diabetic vascular complications, but it is still unknown whether aberrant glucose metabolism leads to defective DNA repair and accounts for hyperglycemia-induced endothelial oxidative str...

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Detalles Bibliográficos
Autores principales: Sun, Dandan, Chen, Shimei, Li, Shenping, Wang, Ning, Zhang, Shuchang, Xu, Li, Zhu, Shaopin, Li, Huiming, Gu, Qing, Xu, Xun, Wei, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803794/
https://www.ncbi.nlm.nih.gov/pubmed/36577299
http://dx.doi.org/10.1016/j.redox.2022.102589

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