Auto-antibodies against type I IFNs in > 10% of critically ill COVID-19 patients: a prospective multicentre study

BACKGROUND: Auto-antibodies (auto-Abs) neutralizing type I interferons (IFN) have been found in about 15% of critical cases COVID-19 pneumonia and less than 1% of mild or asymptomatic cases. Determining whether auto-Abs influence presentation and outcome of critically ill COVID-19 patients could lea...

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Detalles Bibliográficos
Autores principales: Arrestier, Romain, Bastard, Paul, Belmondo, Thibaut, Voiriot, Guillaume, Urbina, Tomas, Luyt, Charles-Edouard, Gervais, Adrian, Bizien, Lucy, Segaux, Lauriane, Ben Ahmed, Mariem, Bellaïche, Raphaël, Pham, Taï, Ait-Hamou, Zakaria, Roux, Damien, Clere-Jehl, Raphael, Azoulay, Elie, Gaudry, Stéphane, Mayaux, Julien, Fage, Nicolas, Ait-Oufella, Hafid, Moncomble, Elsa, Parfait, Mélodie, Dorgham, Karim, Gorochov, Guy, Mekontso-Dessap, Armand, Canoui-Poitrine, Florence, Casanova, Jean-Laurent, Hue, Sophie, de Prost, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803887/
https://www.ncbi.nlm.nih.gov/pubmed/36586050
http://dx.doi.org/10.1186/s13613-022-01095-5

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