Role of Oncostatin M in the Pathogenesis of Vernal Keratoconjunctivitis: Focus on the Barrier Function of the Epithelium and Interleukin-33 Production by Fibroblasts

PURPOSE: Vernal keratoconjunctivitis (VKC) is a severe, recurrent allergic conjunctivitis. Previously, we found high concentrations of oncostatin M (OSM) in the tears of patients with VKC. Here, we investigated the role of OSM in VKC by focusing on epithelial barrier function and IL-33 production. M...

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Detalles Bibliográficos
Autores principales: Ninomiya, Ishin, Yamatoya, Kenji, Mashimo, Keitaro, Matsuda, Akira, Usui-Ouchi, Ayumi, Araki, Yoshihiko, Ebihara, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804018/
https://www.ncbi.nlm.nih.gov/pubmed/36580308
http://dx.doi.org/10.1167/iovs.63.13.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804018/
https://www.ncbi.nlm.nih.gov/pubmed/36580308
http://dx.doi.org/10.1167/iovs.63.13.26

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