Netrin‐1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway

AIM: We aimed to investigate the regulatory role of Netrin‐1 (NTN1) in ferroptosis after traumatic brain injury (TBI) in mice. METHODS: We assessed the expression pattern of NTN1 by RT–PCR, western blot, and immunofluorescence after establishing the TBI model in mice. After treatment with NTN1 shRNA...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanda, Lan, Jin, Zhao, Dongxu, Ruan, Cijie, Zhou, Jue, Tan, Haoyuan, Bao, Yinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804081/
https://www.ncbi.nlm.nih.gov/pubmed/36468399
http://dx.doi.org/10.1111/cns.13997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804081/
https://www.ncbi.nlm.nih.gov/pubmed/36468399
http://dx.doi.org/10.1111/cns.13997

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