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Multiple drug transporters contribute to the brain transfer of levofloxacin

AIMS: The aim of this study was to assess the influence of the major transporters at blood–brain barrier and blood–cerebrospinal fluid barrier on levofloxacin (LVFX) pharmacokinetics in rat. To explore the different effects of transporters on drug concentrations in cerebrospinal fluid (CSF) and brai...

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Detalles Bibliográficos
Autores principales:	Cen, Yuying, Shan, Yuheng, Zhao, Jiahua, Xu, Xiaojiao, Nie, Zhiyong, Zhang, Jiatang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804084/ https://www.ncbi.nlm.nih.gov/pubmed/36253925 http://dx.doi.org/10.1111/cns.13989

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