Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress

The function of the cancer-associated lncRNA Malat1 during aging is as-of-yet uncharacterized. Here, we show that Malat1 interacts with Nucleophosmin (NPM) in young mouse brain, and with Lamin A/C, hnRNP C, and KAP1 with age. RNA-seq and RT-qPCR reveal a persistent expression of Malat1_2 (the 3’isof...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghanam, Amr. R., Ke, Shengwei, Wang, Shujuan, Elgendy, Ramy, Xie, Chenyao, Wang, Siqi, Zhang, Ran, Wei, Min, Liu, Weiguang, Cao, Jun, Zhang, Yan, Zhang, Zhi, Xue, Tian, Zheng, Yong, Song, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804114/
https://www.ncbi.nlm.nih.gov/pubmed/36594014
http://dx.doi.org/10.1016/j.isci.2022.105740

Ejemplares similares

Ejemplares similares