Diverse effector and regulatory functions of fibro/adipogenic progenitors during skeletal muscle fibrosis in muscular dystrophy

Fibrosis is a prominent pathological feature of skeletal muscle in Duchenne muscular dystrophy (DMD). The commonly used disease mouse model, mdx(5cv), displays progressive fibrosis in the diaphragm but not limb muscles. We use single-cell RNA sequencing to determine the cellular expression of the ge...

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Detalles Bibliográficos
Autores principales: Wang, Xingyu, Chen, Jianming, Homma, Sachiko T., Wang, Yinhang, Smith, Gregory R., Ruf-Zamojski, Frederique, Sealfon, Stuart C., Zhou, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804115/
https://www.ncbi.nlm.nih.gov/pubmed/36594034
http://dx.doi.org/10.1016/j.isci.2022.105775

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