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Osteopontin associates with brain T(RM)-cell transcriptome and compartmentalization in donors with and without multiple sclerosis

The human brain is populated by perivascular T cells with a tissue-resident memory T (T(RM))-cell phenotype, which in multiple sclerosis (MS) associate with lesions. We investigated the transcriptional and functional profile of freshly isolated T cells from white and gray matter. RNA sequencing of C...

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Detalles Bibliográficos
Autores principales:	Hsiao, Cheng-Chih, Engelenburg, Hendrik J., Jongejan, Aldo, Zhu, Jing, Zhang, Baohong, Mingueneau, Michael, Moerland, Perry D., Huitinga, Inge, Smolders, Joost, Hamann, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804143/ https://www.ncbi.nlm.nih.gov/pubmed/36594029 http://dx.doi.org/10.1016/j.isci.2022.105785

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