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Cocaine-regulated trafficking of dopamine transporters in cultured neurons revealed by a pH sensitive reporter
Cocaine acts by inhibiting plasma membrane dopamine transporter (DAT) function and altering its surface expression. The precise manner and mechanism by which cocaine regulates DAT trafficking, especially at neuronal processes, are poorly understood. In this study, we engineered and validated the use...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804146/ https://www.ncbi.nlm.nih.gov/pubmed/36594015 http://dx.doi.org/10.1016/j.isci.2022.105782 |