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Cocaine-regulated trafficking of dopamine transporters in cultured neurons revealed by a pH sensitive reporter

Cocaine acts by inhibiting plasma membrane dopamine transporter (DAT) function and altering its surface expression. The precise manner and mechanism by which cocaine regulates DAT trafficking, especially at neuronal processes, are poorly understood. In this study, we engineered and validated the use...

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Detalles Bibliográficos
Autores principales: Saenz, Jacqueline, Yao, Oscar, Khezerlou, Elnaz, Aggarwal, Meha, Zhou, Xiaofeng, Barker, David J., DiCicco-Bloom, Emanuel, Pan, Ping-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804146/
https://www.ncbi.nlm.nih.gov/pubmed/36594015
http://dx.doi.org/10.1016/j.isci.2022.105782