Genetic interaction between Scn8a and potassium channel genes Kcna1 and Kcnq2

Voltage‐gated sodium and potassium channels regulate the initiation and termination of neuronal action potentials. Gain‐of‐function mutations of sodium channel Scn8a and loss‐of‐function mutations of potassium channels Kcna1 and Kcnq2 increase neuronal activity and lead to seizure disorders. We test...

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Detalles Bibliográficos
Autores principales: Hill, Sophie F., Ziobro, Julie M., Jafar‐Nejad, Paymaan, Rigo, Frank, Meisler, Miriam H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804156/
https://www.ncbi.nlm.nih.gov/pubmed/35892317
http://dx.doi.org/10.1111/epi.17374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804156/
https://www.ncbi.nlm.nih.gov/pubmed/35892317
http://dx.doi.org/10.1111/epi.17374

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