Cargando…
Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors
Transfusion of donor‐derived red blood cells (RBCs) is the most common form of cell therapy. Production of transfusion‐ready cultured RBCs (cRBCs) is a promising replacement for the current, fully donor‐dependent therapy. A single transfusion unit, however, contains 2 × 10(12) RBC, which requires la...
Autores principales: | Gallego‐Murillo, Joan Sebastián, Iacono, Giulia, van der Wielen, Luuk A. M., van den Akker, Emile, von Lindern, Marieke, Wahl, Sebastian Aljoscha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804173/ https://www.ncbi.nlm.nih.gov/pubmed/35879812 http://dx.doi.org/10.1002/bit.28193 |
Ejemplares similares
-
Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells
por: Gallego-Murillo, Joan Sebastián, et al.
Publicado: (2023) -
Mechanical Stress Induces Ca(2+)-Dependent Signal Transduction in Erythroblasts and Modulates Erythropoiesis
por: Aglialoro, Francesca, et al.
Publicado: (2021) -
Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts
por: Heshusius, Steven, et al.
Publicado: (2022) -
The productivity limit of manufacturing blood cell therapy in scalable stirred bioreactors
por: Bayley, Rachel, et al.
Publicado: (2017) -
Influence of shear force on ex vivo expansion of hematopoietic model cells in a stirred tank bioreactor
por: Mohseni, Sofia, et al.
Publicado: (2023)