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Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors

Transfusion of donor‐derived red blood cells (RBCs) is the most common form of cell therapy. Production of transfusion‐ready cultured RBCs (cRBCs) is a promising replacement for the current, fully donor‐dependent therapy. A single transfusion unit, however, contains 2 × 10(12) RBC, which requires la...

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Detalles Bibliográficos
Autores principales: Gallego‐Murillo, Joan Sebastián, Iacono, Giulia, van der Wielen, Luuk A. M., van den Akker, Emile, von Lindern, Marieke, Wahl, Sebastian Aljoscha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804173/
https://www.ncbi.nlm.nih.gov/pubmed/35879812
http://dx.doi.org/10.1002/bit.28193

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