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Total Chemical Synthesis of a Functionalized GFP Nanobody

Chemical protein synthesis has proven to be a powerful tool to access homogenously modified proteins. The chemical synthesis of nanobodies (Nb) would create possibilities to design tailored Nbs with a range of chemical modifications such as tags, linkers, reporter groups, and subsequently, Nb‐drug c...

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Detalles Bibliográficos
Autores principales: Huppelschoten, Yara, Elhebieshy, Angela F., Hameed, Dharjath S., Sapmaz, Aysegul, Buchardt, Jens, Nielsen, Thomas E., Ovaa, Huib, van der Heden van Noort, Gerbrand J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804225/
https://www.ncbi.nlm.nih.gov/pubmed/35920208
http://dx.doi.org/10.1002/cbic.202200304