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PTH1R translocation to primary cilia in mechanically‐stimulated ostecytes prevents osteoclast formation via regulation of CXCL5 and IL‐6 secretion

Osteocytes respond to mechanical forces controlling osteoblast and osteoclast function. Mechanical stimulation decreases osteocyte apoptosis and promotes bone formation. Primary cilia have been described as potential mechanosensors in bone cells. Certain osteogenic responses induced by fluid flow (F...

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Detalles Bibliográficos
Autores principales: Tirado‐Cabrera, Irene, Martin‐Guerrero, Eduardo, Heredero‐Jimenez, Sara, Ardura, Juan A., Gortázar, Arancha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804361/
https://www.ncbi.nlm.nih.gov/pubmed/35933642
http://dx.doi.org/10.1002/jcp.30849