A pulmonary endothelial amplification loop aggravates ex‐vivo transfusion‐related acute lung injury via increased toll‐like receptor 4 and intra‐cellular adhesion molecule‐1 expression

BACKGROUND: Transfusion‐Related Acute Lung Injury (TRALI) is a life‐threatening complication of blood transfusions characterized by pulmonary endothelial cell damage and edema, with a high incidence in critically ill patients. The pathophysiology of TRALI is unresolved, but can generally be hypothes...

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Detalles Bibliográficos
Autores principales: Morsing, Sofia K. H., Zeeuw van der Laan, Eveline, van Stalborch, Annemarieke D., van Buul, Jaap D., Kapur, Rick, Vlaar, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804532/
https://www.ncbi.nlm.nih.gov/pubmed/36004763
http://dx.doi.org/10.1111/trf.17076

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