Cargando…

Simplified and accessible [(18)F]F‐AraG synthesis procedure for preclinical PET

The PET tracer [(18)F]F‐AraG, an arabinosyl guanine analog, has shown promise for visualizing activated T cells in multiple diseases. Herein, a practitioner's protocol is described, in which the PET tracer is prepared using minimal equipment and manual actions, making it widely accessible for p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Högnäsbacka, Antonia A., Cortés González, Miguel A., Halldin, Christer, Schou, Magnus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Practitioner Protocol–Synthesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804570/ https://www.ncbi.nlm.nih.gov/pubmed/35980801 http://dx.doi.org/10.1002/jlcr.3997

Ejemplares similares

Biodistribution of a Mitochondrial Metabolic Tracer, [(18)F]F-AraG, in Healthy Volunteers
por: Levi, Jelena, et al.
Publicado: (2022)

An improved radiosynthesis of [(18)F]FAraG, a PET radiotracer for imaging T‐cell activation
por: Holt, Daniel P., et al.
Publicado: (2022)

Total-body Dynamic Imaging and Kinetic Modeling of (18)F-AraG in Healthy Individuals and a Non-Small Cell Lung Cancer Patient Undergoing Anti-PD-1 Immunotherapy
por: Omidvari, Negar, et al.
Publicado: (2023)

PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [(18)F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain
por: Varnäs, Katarina, et al.
Publicado: (2023)

“In‐loop” carbonylation—A simplified method for carbon‐11 labelling of drugs and radioligands
por: Ferrat, Mélodie, et al.
Publicado: (2020)

Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: (18)F-AZD9272
por: Nag, Sangram, et al.
Publicado: (2020)

Microsome Mediated in Vitro Metabolism: A Convenient Method for the Preparation of the PET Radioligand Metabolite [(18)F]FE-PE2I-OH for Translational Dopamine Transporter Imaging
por: Schou, Magnus, et al.
Publicado: (2023)

Synthesis of [4S‐(2)H]NADH, [4R‐(2)H]NADH, [4‐(2)H(2)]NADH and [4‐(2)H]NAD(+) cofactors through heterogeneous biocatalysis in heavy water
por: Rowbotham, Jack S., et al.
Publicado: (2021)

Development of an automated production process of [(64)Cu][Cu (ATSM)] for positron emission tomography imaging and theranostic applications
por: Liu, Tengzhi, et al.
Publicado: (2022)

Synthesis of [(2)H(5)]baricitinib via [(2)H(5)]ethanesulfonyl chloride
por: Jansen‐van Vuuren, Ross D., et al.
Publicado: (2022)

PET Imaging of VMAT2 with the Novel Radioligand [(18)F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [(11)C]DTBZ and [(18)F]FE-DTBZ
por: Nag, Sangram, et al.
Publicado: (2021)

(18) F-click labeling and preclinical evaluation of a new (18) F-folate for PET imaging
por: Schieferstein, Hanno, et al.
Publicado: (2013)

A simplified approach to detect a significant carbon dioxide reduction by phytoplankton in lakes and rivers on a regional and global scale
por: Engel, Fabian, et al.
Publicado: (2020)

Reliability of dopamine transporter PET measurements with [(18)F]FE-PE2I in patients with Parkinson’s disease
por: Kerstens, Vera S., et al.
Publicado: (2020)

Decreased defluorination using the novel beta-cell imaging agent [(18)F]FE-DTBZ-d4 in pigs examined by PET
por: Jahan, Mahabuba, et al.
Publicado: (2011)

Preclinical Evaluation of [(18)F]FACH in Healthy Mice and Piglets: An (18)F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET
por: Gündel, Daniel, et al.
Publicado: (2021)

Easy method to simplify “freehand” subaxial cervical pedicle screw insertion
por: Burcev, Alexander V, et al.
Publicado: (2017)

[(18)F]FE-PE2I DAT correlates with Parkinson’s disease duration, stage, and rigidity/bradykinesia scores: a PET radioligand validation study
por: Kerstens, Vera S., et al.
Publicado: (2023)

Fates beyond traits: ecological consequences of human-induced trait change
por: Palkovacs, Eric P, et al.
Publicado: (2012)

Genetic erosion impedes adaptive responses to stressful environments
por: Bijlsma, R, et al.
Publicado: (2012)

The implications of nongenetic inheritance for evolution in changing environments
por: Bonduriansky, Russell, et al.
Publicado: (2012)

Evolutionary principles and their practical application
por: Hendry, Andrew P, et al.
Publicado: (2011)

Evolution and behavioural responses to human-induced rapid environmental change
por: Sih, Andrew, et al.
Publicado: (2011)

Incorporating evolutionary principles into environmental management and policy
por: Lankau, Richard, et al.
Publicado: (2011)

Newly rare or newly common: evolutionary feedbacks through changes in population density and relative species abundance, and their management implications
por: Lankau, Richard A, et al.
Publicado: (2011)

The role of adaptive trans-generational plasticity in biological invasions of plants
por: Dyer, Andrew R, et al.
Publicado: (2010)

Life history change in commercially exploited fish stocks: an analysis of trends across studies
por: Sharpe, Diana M T, et al.
Publicado: (2009)

Group selection and social evolution in domesticated animals
por: Wade, Michael J, et al.
Publicado: (2010)

Evolutionary ecology of insect adaptation to Bt crops
por: Carrière, Yves, et al.
Publicado: (2010)

Evolutionary process of Bos taurus cattle in favourable versus unfavourable environments and its implications for genetic selection
por: O'Neill, Christopher J, et al.
Publicado: (2010)

Exploring the evolutionary ecology of fungal endophytes in agricultural systems: using functional traits to reveal mechanisms in community processes
por: Saunders, Megan, et al.
Publicado: (2010)

Crops gone wild: evolution of weeds and invasives from domesticated ancestors
por: Ellstrand, Norman C, et al.
Publicado: (2010)

Reciprocal insights into adaptation from agricultural and evolutionary studies in tomato
por: Moyle, Leonie C, et al.
Publicado: (2010)

Evolutionary response of landraces to climate change in centers of crop diversity
por: Mercer, Kristin L, et al.
Publicado: (2010)

Evolutionary ecology of mycorrhizal functional diversity in agricultural systems
por: Verbruggen, Erik, et al.
Publicado: (2010)

Common garden comparisons of native and introduced plant populations: latitudinal clines can obscure evolutionary inferences
por: Colautti, Robert I, et al.
Publicado: (2009)

Seed supply for broadscale restoration: maximizing evolutionary potential
por: Broadhurst, Linda M, et al.
Publicado: (2008)

How well can captive breeding programs conserve biodiversity? A review of salmonids
por: Fraser, Dylan J
Publicado: (2008)

Adaptation, migration or extirpation: climate change outcomes for tree populations
por: Aitken, Sally N, et al.
Publicado: (2008)

Virulence and resistance in a mosquito–microsporidium interaction
por: Michalakis, Yannis, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_qd3vmf71kg7firi2b86ldeen7u