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Beneficial metabolic effects of recurrent periods of beta‐cell rest and stimulation using stable neuropeptide Y1 and glucagon‐like peptide‐1 receptor agonists

AIM: To examine whether sequential administration of (d‐Arg(35))‐sea lamprey peptide tyrosine tyrosine (1–36) (SL‐PYY) and the glucagon‐like peptide‐1 (GLP‐1) mimetic, liraglutide, has beneficial effects in diabetes. METHODS: SL‐PYY is an enzymatically stable neuropeptide Y1 receptor (NPY1R) agonist...

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Detalles Bibliográficos
Autores principales: Tanday, Neil, Lafferty, Ryan A., Flatt, Peter R., Irwin, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804730/
https://www.ncbi.nlm.nih.gov/pubmed/35848461
http://dx.doi.org/10.1111/dom.14821