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3′RNA and whole‐genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1

Uterine leiomyomas, or fibroids, are very common smooth muscle tumors that arise from the myometrium. They can be divided into distinct molecular subtypes. We have previously shown that 3′RNA‐sequencing is highly effective in classifying archival formalin‐fixed paraffin‐embedded (FFPE) leiomyomas ac...

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Detalles Bibliográficos
Autores principales: Jokinen, Vilja, Mehine, Miika, Reinikka, Siiri, Khamaiseh, Sara, Ahvenainen, Terhi, Äyräväinen, Anna, Härkki, Päivi, Bützow, Ralf, Pasanen, Annukka, Vahteristo, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804854/
https://www.ncbi.nlm.nih.gov/pubmed/35822448
http://dx.doi.org/10.1002/gcc.23088

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