DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)

A non‐synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP‐dependent mMEP‐2* locus in Atlantic salmon (Salmo salar L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mo...

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Detalles Bibliográficos
Autores principales: Taggart, John B., Leaver, Michael J., Bekaert, Michaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804884/
https://www.ncbi.nlm.nih.gov/pubmed/35912429
http://dx.doi.org/10.1111/jfb.15182
Descripción
Sumario:A non‐synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP‐dependent mMEP‐2* locus in Atlantic salmon (Salmo salar L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mobility of the two allozyme alleles, whereas allozyme and SNP assays revealed genotyping concordance in 257 of 258 individuals. A single mismatch, homozygous allozyme vs. heterozygote SNP, suggests the presence of a second, less common null allele.

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