DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)

A non‐synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP‐dependent mMEP‐2* locus in Atlantic salmon (Salmo salar L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mo...

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Detalles Bibliográficos
Autores principales: Taggart, John B., Leaver, Michael J., Bekaert, Michaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804884/
https://www.ncbi.nlm.nih.gov/pubmed/35912429
http://dx.doi.org/10.1111/jfb.15182
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author Taggart, John B.
Leaver, Michael J.
Bekaert, Michaël
author_facet Taggart, John B.
Leaver, Michael J.
Bekaert, Michaël
author_sort Taggart, John B.
collection PubMed
description A non‐synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP‐dependent mMEP‐2* locus in Atlantic salmon (Salmo salar L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mobility of the two allozyme alleles, whereas allozyme and SNP assays revealed genotyping concordance in 257 of 258 individuals. A single mismatch, homozygous allozyme vs. heterozygote SNP, suggests the presence of a second, less common null allele.
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spelling pubmed-98048842023-01-06 DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.) Taggart, John B. Leaver, Michael J. Bekaert, Michaël J Fish Biol Brief Communications A non‐synonymous single nucleotide polymorphism (SNP) underlies a diallelic allozyme polymorphism at the mitochondrial NADP‐dependent mMEP‐2* locus in Atlantic salmon (Salmo salar L.). The resultant amino acid substitution, which alters the charge of the allelic products, matches the differential mobility of the two allozyme alleles, whereas allozyme and SNP assays revealed genotyping concordance in 257 of 258 individuals. A single mismatch, homozygous allozyme vs. heterozygote SNP, suggests the presence of a second, less common null allele. Blackwell Publishing Ltd 2022-08-14 2022-11 /pmc/articles/PMC9804884/ /pubmed/35912429 http://dx.doi.org/10.1111/jfb.15182 Text en © 2022 The Authors. Journal of Fish Biology published by John Wiley & Sons Ltd on behalf of Fisheries Society of the British Isles. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communications
Taggart, John B.
Leaver, Michael J.
Bekaert, Michaël
DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)
title DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)
title_full DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)
title_fullStr DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)
title_full_unstemmed DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)
title_short DNA polymorphism underlying allozyme variation at a malic enzyme locus (mMEP‐2*) in Atlantic salmon (Salmo salar L.)
title_sort dna polymorphism underlying allozyme variation at a malic enzyme locus (mmep‐2*) in atlantic salmon (salmo salar l.)
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804884/
https://www.ncbi.nlm.nih.gov/pubmed/35912429
http://dx.doi.org/10.1111/jfb.15182
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