Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells

The receptor Triggering Receptor Expressed on Myeloid cells 2 (TREM2) is associated with several neurodegenerative diseases including Alzheimer's Disease and TREM2 stimulation represents a novel therapeutic opportunity. TREM2 can be activated by antibodies targeting the stalk region, most likel...

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Detalles Bibliográficos
Autores principales: Boudesco, Christophe, Nonneman, Annelies, Cinti, Alessandro, Picardi, Paola, Redaelli, Loredana, Swijsen, Sofie, Roewe, Julian, Reinhardt, Peter, Ibach, Melanie, Walter, Jochen, Pocock, Jennifer M., Ren, Yi, Driguez, Pierre‐Alexandre, Dargazanli, Gihad, Eyquem, Stephanie, Proto, Jonathan, Flores‐Morales, Amilcar, Pradier, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804933/
https://www.ncbi.nlm.nih.gov/pubmed/35912412
http://dx.doi.org/10.1002/glia.24252

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