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Enhancing the Peroxygenase Activity of a Cofactor‐Independent Peroxyzyme by Directed Evolution Enabling Gram‐Scale Epoxide Synthesis
Peroxygenases selectively incorporate oxygen into organic molecules making use of the environmentally friendly oxidant H(2)O(2) with water being the sole by‐product. These biocatalysts can provide ‘green’ routes for the synthesis of enantioenriched epoxides, which are fundamental intermediates in th...
Autores principales: | Sigmund, Marie‐Cathérine, Xu, Guangcai, Grandi, Eleonora, Poelarends, Gerrit J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804992/ https://www.ncbi.nlm.nih.gov/pubmed/35861144 http://dx.doi.org/10.1002/chem.202201651 |
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