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Enhancing the Peroxygenase Activity of a Cofactor‐Independent Peroxyzyme by Directed Evolution Enabling Gram‐Scale Epoxide Synthesis

Peroxygenases selectively incorporate oxygen into organic molecules making use of the environmentally friendly oxidant H(2)O(2) with water being the sole by‐product. These biocatalysts can provide ‘green’ routes for the synthesis of enantioenriched epoxides, which are fundamental intermediates in th...

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Detalles Bibliográficos
Autores principales: Sigmund, Marie‐Cathérine, Xu, Guangcai, Grandi, Eleonora, Poelarends, Gerrit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804992/
https://www.ncbi.nlm.nih.gov/pubmed/35861144
http://dx.doi.org/10.1002/chem.202201651

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