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Targeted Enzymatic VLP‐Nanoreactors with β‐Glucocerebrosidase Activity as Potential Enzyme Replacement Therapy for Gaucher's Disease
Gaucher disease is a genetic disorder and the most common lysosomal disease caused by the deficiency of enzyme β‐glucocerebrosidase (GCase). Although enzyme replacement therapy (ERT) is successfully applied using mannose‐exposed conjugated glucocerebrosidase, the lower stability of the enzyme in blo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804995/ https://www.ncbi.nlm.nih.gov/pubmed/35918294 http://dx.doi.org/10.1002/cmdc.202200384 |