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Targeted Enzymatic VLP‐Nanoreactors with β‐Glucocerebrosidase Activity as Potential Enzyme Replacement Therapy for Gaucher's Disease

Gaucher disease is a genetic disorder and the most common lysosomal disease caused by the deficiency of enzyme β‐glucocerebrosidase (GCase). Although enzyme replacement therapy (ERT) is successfully applied using mannose‐exposed conjugated glucocerebrosidase, the lower stability of the enzyme in blo...

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Detalles Bibliográficos
Autores principales: Chauhan, Kanchan, Olivares‐Medina, Cindy N., Villagrana‐Escareño, Maria V., Juárez‐Moreno, Karla, Cadena‐Nava, Rubén D., Rodríguez‐Hernández, Ana G., Vazquez‐Duhalt, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804995/
https://www.ncbi.nlm.nih.gov/pubmed/35918294
http://dx.doi.org/10.1002/cmdc.202200384

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