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PARP1 inhibition enhances reactive oxygen species on gut microbiota

Poly(ADP‐ribose) polymerase 1 (PARP1) plays a key role in genome stability by modulating DNA‐damage responses. Activated by DNA interruptions through ultraviolet (UV) exposure, PARylation is synthesized by PARP1 and serves as a survival mechanism for cancer and metabolic diseases. Several strategies...

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Detalles Bibliográficos
Autores principales:	Zhuang, Yixiao, Wang, Hui, Ding, Jiyang, Zhang, Xinyi, Liu, Xiaoyu, Zhang, Shuai, Xing, Xiaorui, Kaudimba, Keneilwe Kenny, He, Muyang, Zhang, Shuang, Guo, Shanshan, Kong, Xingxing, Jin, Li, Liu, Tiemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805012/ https://www.ncbi.nlm.nih.gov/pubmed/35998296 http://dx.doi.org/10.1002/jcp.30861

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