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Tight junction formation by a claudin mutant lacking the COOH‐terminal PDZ domain‐binding motif
Claudin‐based tight junctions (TJs) are formed at the most apical part of cell–cell contacts in epithelial cells. Previous studies suggest that scaffolding proteins ZO‐1 and ZO‐2 (ZO proteins) determine the location of TJs by interacting with claudins, but this idea is not conclusive. To address the...
Autores principales: | Fujiwara, Sachiko, Nguyen, Thanh Phuong, Furuse, Kyoko, Fukazawa, Yugo, Otani, Tetsuhisa, Furuse, Mikio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805020/ https://www.ncbi.nlm.nih.gov/pubmed/35945631 http://dx.doi.org/10.1111/nyas.14881 |
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