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Tight junction formation by a claudin mutant lacking the COOH‐terminal PDZ domain‐binding motif

Claudin‐based tight junctions (TJs) are formed at the most apical part of cell–cell contacts in epithelial cells. Previous studies suggest that scaffolding proteins ZO‐1 and ZO‐2 (ZO proteins) determine the location of TJs by interacting with claudins, but this idea is not conclusive. To address the...

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Detalles Bibliográficos
Autores principales: Fujiwara, Sachiko, Nguyen, Thanh Phuong, Furuse, Kyoko, Fukazawa, Yugo, Otani, Tetsuhisa, Furuse, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805020/
https://www.ncbi.nlm.nih.gov/pubmed/35945631
http://dx.doi.org/10.1111/nyas.14881

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