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Whole-blood methylation signatures are associated with and accurately classify multiple sclerosis disease severity

BACKGROUND: The variation in multiple sclerosis (MS) disease severity is incompletely explained by genetics, suggesting genetic and environmental interactions are involved. Moreover, the lack of prognostic biomarkers makes it difficult for clinicians to optimise care. DNA methylation is one epigenet...

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Detalles Bibliográficos
Autores principales:	Campagna, Maria Pia, Xavier, Alexandre, Lea, Rodney A., Stankovich, Jim, Maltby, Vicki E., Butzkueven, Helmut, Lechner-Scott, Jeannette, Scott, Rodney J., Jokubaitis, Vilija G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805090/ https://www.ncbi.nlm.nih.gov/pubmed/36585691 http://dx.doi.org/10.1186/s13148-022-01397-2

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