MicroRNA‐22 suppresses NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokine production by targeting the HIF‐1α and NLRP3 in human dental pulp fibroblasts

AIM: To investigate the synergetic regulatory effect of miR‐22 on HIF‐1α and NLRP3, subsequently regulating the production of the NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokines IL‐1β and IL‐18 in human dental pulp fibroblasts (HDPFs) during the progression of pulpitis. METHODOLO...

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Detalles Bibliográficos
Autores principales: Jiang, Wenkai, Sun, Shukai, Wang, Diya, Qiu, Jun, Song, Ya, Zhang, Qianxia, He, Wenxi, Song, Bing, Zhang, Yaqing, Wang, Shengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Biological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805103/
https://www.ncbi.nlm.nih.gov/pubmed/35979583
http://dx.doi.org/10.1111/iej.13814

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