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The role of the sirtuin family in cartilage and osteoarthritis: molecular mechanisms and therapeutic targets

Osteoarthritis (OA) is mainly characterized by the progressive destruction of articular cartilage. Mounting studies have revealed that disruption of extracellular matrix (ECM) homeostasis, aberrant chondrocyte metabolism, an increase in the number of senescent chondrocytes and abnormal activation of...

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Detalles Bibliográficos
Autores principales:	Sun, Kaibo, Wu, Yuangang, Zeng, Yi, Xu, Jiawen, Wu, Limin, Li, Mingyang, Shen, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805245/ https://www.ncbi.nlm.nih.gov/pubmed/36585687 http://dx.doi.org/10.1186/s13075-022-02983-8

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