Stable production of recombinant SARS-CoV-2 receptor-binding domain in mammalian cells with co-expression of a fluorescent reporter and its validation as antigenic target for COVID-19 serology testing

SARS-CoV-2 receptor binding domain (RBD) recognizes the angiotensin converting enzyme 2 (ACE2) receptor in host cells that enables infection. Due to its antigenic specificity, RBD production is important for development of serological assays. Here we have established a system for stable RBD producti...

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Detalles Bibliográficos
Autores principales: Arias-Arias, Jorge L., Molina-Castro, Silvia E., Monturiol-Gross, Laura, Lomonte, Bruno, Corrales-Aguilar, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805376/
https://www.ncbi.nlm.nih.gov/pubmed/36619904
http://dx.doi.org/10.1016/j.btre.2022.e00780

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