Single-cell resolved ploidy and chromosomal aberrations in nonalcoholic steatohepatitis-(NASH) induced hepatocellular carcinoma and its precursor lesions

Nonalcoholic steatohepatitis (NASH)-induced hepatocellular carcinoma (HCC) and its precursor, nonalcoholic fatty liver disease (NAFLD) are an unmet health issue due to widespread obesity. We assessed copy number changes of genes associated with hepatocarcinogenesis and oxidative pathways at a single...

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Detalles Bibliográficos
Autores principales: Friemel, Juliane, Torres, Irianna, Brauneis, Elizabeth, Thörner, Tim, Schäffer, Alejandro A., Gertz, E. Michael, Grob, Tobias, Seidl, Kati, Weber, Achim, Ried, Thomas, Heselmeyer-Haddad, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805444/
https://www.ncbi.nlm.nih.gov/pubmed/36587184
http://dx.doi.org/10.1038/s41598-022-27173-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805444/
https://www.ncbi.nlm.nih.gov/pubmed/36587184
http://dx.doi.org/10.1038/s41598-022-27173-z

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