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Unbiased pangenome graphs

MOTIVATION: Pangenome variation graphs model the mutual alignment of collections of DNA sequences. A set of pairwise alignments implies a variation graph, but there are no scalable methods to generate such a graph from these alignments. Existing related approaches depend on a single reference, a spe...

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Detalles Bibliográficos
Autores principales: Garrison, Erik, Guarracino, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805579/
https://www.ncbi.nlm.nih.gov/pubmed/36448683
http://dx.doi.org/10.1093/bioinformatics/btac743