Primary midbrain germinoma relapse-free for 5 years: A case report

BACKGROUND: The biology and clinical course of intracranial germinomas differ as per their location of occurrence. Germinoma of the primary midbrain is particularly rare, and its clinical features, treatment strategies, and long-term prognosis remain uncertain. CASE DESCRIPTION: A 39-year-old man wh...

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Autores principales: Oshima, Akito, Kimura, Toshikazu, Akabane, Atsuya, Inoue, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805627/
https://www.ncbi.nlm.nih.gov/pubmed/36600775
http://dx.doi.org/10.25259/SNI_703_2022
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author Oshima, Akito
Kimura, Toshikazu
Akabane, Atsuya
Inoue, Tomohiro
author_facet Oshima, Akito
Kimura, Toshikazu
Akabane, Atsuya
Inoue, Tomohiro
author_sort Oshima, Akito
collection PubMed
description BACKGROUND: The biology and clinical course of intracranial germinomas differ as per their location of occurrence. Germinoma of the primary midbrain is particularly rare, and its clinical features, treatment strategies, and long-term prognosis remain uncertain. CASE DESCRIPTION: A 39-year-old man who had been diagnosed with midbrain germinoma by open biopsy through the occipital transtentorial approach had undergone chemoradiotherapy and achieved 5 years with no recurrence. CONCLUSION: Germinomas should be considered as a differential diagnosis for adolescents and young adult men with mesencephalic tumors, and reliable sampling followed by chemoradiotherapy must be performed.
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spelling pubmed-98056272023-01-03 Primary midbrain germinoma relapse-free for 5 years: A case report Oshima, Akito Kimura, Toshikazu Akabane, Atsuya Inoue, Tomohiro Surg Neurol Int Case Report BACKGROUND: The biology and clinical course of intracranial germinomas differ as per their location of occurrence. Germinoma of the primary midbrain is particularly rare, and its clinical features, treatment strategies, and long-term prognosis remain uncertain. CASE DESCRIPTION: A 39-year-old man who had been diagnosed with midbrain germinoma by open biopsy through the occipital transtentorial approach had undergone chemoradiotherapy and achieved 5 years with no recurrence. CONCLUSION: Germinomas should be considered as a differential diagnosis for adolescents and young adult men with mesencephalic tumors, and reliable sampling followed by chemoradiotherapy must be performed. Scientific Scholar 2022-12-09 /pmc/articles/PMC9805627/ /pubmed/36600775 http://dx.doi.org/10.25259/SNI_703_2022 Text en Copyright: © 2022 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Oshima, Akito
Kimura, Toshikazu
Akabane, Atsuya
Inoue, Tomohiro
Primary midbrain germinoma relapse-free for 5 years: A case report
title Primary midbrain germinoma relapse-free for 5 years: A case report
title_full Primary midbrain germinoma relapse-free for 5 years: A case report
title_fullStr Primary midbrain germinoma relapse-free for 5 years: A case report
title_full_unstemmed Primary midbrain germinoma relapse-free for 5 years: A case report
title_short Primary midbrain germinoma relapse-free for 5 years: A case report
title_sort primary midbrain germinoma relapse-free for 5 years: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805627/
https://www.ncbi.nlm.nih.gov/pubmed/36600775
http://dx.doi.org/10.25259/SNI_703_2022
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