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Discovery of pulmonary fibrosis inhibitor targeting TGF-β RI in Polygonum cuspidatum by high resolution mass spectrometry with in silico strategy

Pulmonary fibrosis (PF) is an irreversible lung disease that is characterized by excessive scar tissue with a poor median survival rate of 2–3 years. The inhibition of transforming growth factor-β receptor type-I (TGF-β RI) by an appropriate drug may provide a promising strategy for the treatment of...

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Detalles Bibliográficos
Autores principales: Xu, Huarong, Qu, Jiameng, Wang, Jian, Han, Kefei, Li, Qing, Bi, Wenchuan, Liu, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805938/
https://www.ncbi.nlm.nih.gov/pubmed/36605575
http://dx.doi.org/10.1016/j.jpha.2020.05.007